Contractile action of yohimbine in the dog basilar artery
نویسندگان
چکیده
منابع مشابه
Histological Study of the Elastic Artery, Muscular Artery, and Their Junction in Neonate Dog
Introduction: We did this study because there were a few studies about aorto-branch junction. Methods: Four light microscope and electron microscope study, the abdominal aorta, renal artery, and the adjoining right and left renal arteries were dissected out from 4 neonate dogs. Results: Based on the results, there is only one cell type in the tunica intima of endothelium in both art...
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We previously suggested that activation of the protein kinase C-mediated contractile system may participate in the occurrence of chronic cerebral vasospasm. In the present study, we compared segments of normal beagle basilar arteries in vitro with segments of arteries undergoing chronic vasospasm to determine the responsiveness to various agonists such as serotonin, prostaglandin F2 alpha, and ...
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BACKGROUND AND PURPOSE The level of platelet-derived growth factor (PDGF) in cerebrospinal fluid is elevated in subarachnoid hemorrhage (SAH). Therefore, the contractile effect of PDGF on the basilar artery was examined in SAH. METHODS A rabbit double-hemorrhage SAH model was used. In the medial layers of the control basilar artery, PDGF had no effect on contraction up to 1 nmol/L, whereas 3 ...
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One of the locations of renal artery atherosclerosis is at the orifice of the renal artery, therefore thestructure of this orifice was assessed in 6 normal, adult male dogs by light microscopy (LM) andtransmission electron microscopy (TEM). For the LM study, processed tissues were embedded in paraffinand sectioned serially into 6-μm thickness. Sections were stained with orcein. For the TEM stud...
متن کاملCharacterization of norepinephrine-induced contractile response in isolated rabbit basilar artery.
It is well known that a-adrenoceptors have been classified into the a1-type in postsynaptic sites and the a2-type in presynaptic sites (1). Prazosin and yohimbine are selective an tagonists of a1 and a2-adrenoceptors, re spectively (2). Norepinephrine (NE) exerts a non-selective agonistic action at each type of a-adrenoceptors (3, 4). Recent reports present evidence that postsynaptic a2 as well...
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ژورنال
عنوان ژورنال: Japanese Journal of Pharmacology
سال: 1984
ISSN: 0021-5198
DOI: 10.1016/s0021-5198(19)62796-4